Identificacion Principal del registro INGC-EBK-000603

Control Number Identifier AR-LpUFI

LAST MODIFICATION DATE 20160831172618

CONTROL FIELD cr nn 008mamaa

CONTROL FIELD 130717s2014 gw | s |||| 0|eng d

a International Standard Book Number 9783642285547

a Standard number or code 10.1007/978-3-642-28554-7

a Title Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes

h Medium [libro electrónico] : ;

b Remainder of title From Bioinformatics to Molecular Quantum Mechanics /

c Statement of responsibility, etc edited by Adam Liwo.

a Place of publication, distribution, etc Berlin, Heidelberg :

b Name of publisher, distributor, etc Springer Berlin Heidelberg :

b Name of publisher, distributor, etc Imprint: Springer,

c Date of publication, distribution, etc 2014.

a Extent xiv, 810 p. :

b Other physical details il.

a Series statement Springer Series in Bio-/Neuroinformatics,

x International Standard Serial Number 2193-9349 ;

v Volume number/sequential designation 1

a Formatted contents note Molecular simulations: methodology -- Molecular simulations: applications -- Use of structural database or experimental information in modeling protein structure and dynamics -- Applications of molecular quantum mechanics.

a Summary, etc Since the second half of the 20th century machine computations have played a critical role in science and engineering. Computer-based techniques have become especially important in molecular biology, since they often represent the only viable way to gain insights into the behavior of a biological system as a whole. The complexity of biological systems, which usually needs to be analyzed on different time- and size-scales and with different levels of accuracy, requires the application of different approaches, ranging from comparative analysis of sequences and structural databases, to the analysis of networks of interdependence between cell components and processes, through coarse-grained modeling to atomically detailed simulations, and finally to molecular quantum mechanics. This book provides a comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes. The twenty-two chapters, written by scientists from all over the world, address the theory and practice of computer simulation techniques in the study of biological phenomena. The chapters are grouped into four thematic sections dealing with the following topics: the methodology of molecular simulations; applications of molecular simulations; bioinformatics methods and use of experimental information in molecular simulations; and selected applications of molecular quantum mechanics. The book includes an introductory chapter written by Harold A. Scheraga, one of the true pioneers in simulation studies of biomacromolecules.

a Topical term or geographic name as entry element Chemistry, Physical and theoretical.

a Topical term or geographic name as entry element Bioinformatics.

a Topical term or geographic name as entry element Proteins.

a Topical term or geographic name as entry element Engineering.

a Topical term or geographic name as entry element Computational Intelligence.

a Topical term or geographic name as entry element Computational Biology/Bioinformatics.

a Topical term or geographic name as entry element Protein Science.

a Topical term or geographic name as entry element Theoretical and Computational Chemistry.

a Topical term or geographic name as entry element Mechanics.

a Personal name Liwo, Adam,

e Relator term ed.

u Uniform Resource Identifier (R) http://dx.doi.org/10.1007/978-3-642-28554-7

c item type EBK

a descripción COM